The Disease
Anti-IgLON5 disease is a neurological disease at the
crossroads of autoimmunity and neurodegeneration
Anti-IgLON5 disease is a neurological disease in which the body’s own defenses mistakenly attack the neurons. In this condition, the immune system targets a brain protein called IgLON5, which function is unclear.
For reasons that are still unknown, this immune attack (autoimmunity) leads to brain degeneration, with changes that resemble those seen in Alzheimer’s disease (neurodegeneration).
This unusual combination of autoimmunity and neurodegeneration makes Anti-IgLON5 disease unique.
Our goal is to better understand how immune attacks on the brain can lead to neurodegeneration. By studying this rare but life-threatening disease, we hope to uncover mechanisms that may also be relevant to more common neurodegenerative disorders, ultimately helping to improve diagnosis and treatment for many patients.
WORK WITH US
IGNITION offers a fully funded Marie Skłodowska-Curie Actions – Doctoral Networks (MSCA-DN) training program, empowering the next generation of researchers to tackle immune-mediated neurodegeneration and develop transformative solutions.
CANDIDATES
Doctoral Candidates
BENEFICIARIES
World-leading Beneficiaries
COUNTRIES
European Countries
WORK WITH US
IGNITION offers a fully funded Marie Skłodowska-Curie Actions – Doctoral Networks (MSCA-DN) training program, empowering the next generation of researchers to tackle immune-mediated neurodegeneration and develop transformative solutions.
CANDIDATES
Doctoral Candidates
BENEFICIARIES
World-leading Beneficiaries
COUNTRIES
European Countries
CONSORTIUM
IGNITION brings together a multisectorial and multidisciplinary team of leading experts
to train the new generation of young researchers, equipping them to become the future leaders
in neuroimmunology and neurodegenerative disorders.
